MCP for Gastrointestinal Support

Low Molecular Weight Citrus Pectin, also known as Modified Citrus Pectin (MCP) or Low Molecular Citrus Pectin (LCP), is a galactose-rich, small-molecule, water-soluble dietary fiber polysaccharide extracted from the peel and inner membrane of citrus fruits (lemon, orange, mandarin, pomelo, etc.) using advanced biological enzymatic hydrolysis technology.

Zhejiang Gold Kropn Bio-tech Co., Ltd. has collaborated with Zhejiang University, Tianjin University, Fudan University, Xinxiang Medical University, and other institutions on research into MCP production processes and functional studies, and has been granted multiple national invention patents. Studies have shown that MCP of varying molecular weights and degrees of esterification can help boost human immunity, inhibit tumor cell activity, remove heavy metals, and relieve constipation, among other functions. The company is currently the only MCP manufacturer in Asia, and one of only two in the world.

Low molecular weight pectin (MCP) contains over 80% water-soluble dietary fiber and provides excellent bidirectional regulation of gastrointestinal health - helping to relieve conditions such as constipation while also addressing issues such as diarrhea - with the added benefit of being safe and free of rebound effects.

Strong water-holding capacity of MCP MCP can absorb more than 20 times its own weight in water, and retains that water strongly. This helps prevent stool from hardening in the intestines, thereby helping to prevent constipation.

Gelling properties of MCP Upon entering the gastrointestinal tract, MCP absorbs water and, under the pH conditions of body fluids, forms a gel filtration system that can alter the proportion of nutrients absorbed by the body and adsorb and remove toxins, helping to prevent diarrhea caused by pathogenic factors.

Film-forming properties of MCP MCP is a macromolecular substance that readily forms films. Within the gastrointestinal tract it forms a molecular film that coats the stomach wall, helping protect the gastric and intestinal mucosa from damage, helping prevent conditions such as enteritis and gastric ulcers from worsening, and supporting the recovery of damaged mucosa.

Chelating properties of MCP MCP has a strong chelating effect on heavy metals such as lead, cadmium, and arsenic, which can effectively help prevent damage to the body from these heavy metals, support immune function, and help prevent gastrointestinal issues such as diarrhea, bloating, and constipation caused by reduced immune function.

Microbial degradation properties of MCP MCP is a water-soluble dietary fiber. After entering the large intestine, a large proportion of it is broken down and serves as a nutrient source for gut microbiota. The short-chain fatty acids generated through microbial fermentation can also lower colonic pH, promoting the proliferation of beneficial bacteria, helping beneficial bacteria maintain a dominant position in the gut, and helping lower the likelihood of gastrointestinal disease.

MCP's positive effect on intestinal morphology Research has found that MCP intake can alter intestinal morphology, increasing the height of small intestinal villi and the depth of intestinal crypts, and increasing the mucosal muscle area of the ileum and mid-colon. This is because short-chain fatty acids produced through MCP fermentation promote compensatory growth of the intestines. As a result, long-term intake of MCP may help support gastrointestinal regulation and improve the condition of the skin.

MCP is recognized by the Food and Agriculture Organization (FAO) and the World Health Organization (WHO) as a safe ingredient with no specified upper limit on daily human intake.

Gold Kropn uses imported lemon peel from Argentina, which undergoes rinsing, dehydration, pesticide residue removal, and heavy metal testing at every stage of processing.

Production takes place in a Class 100,000 GMP-certified clean workshop, applying pharmaceutical-grade standards to food production, with strict controls at every step of the process. The company holds certifications including GMP, ISO 9001, ISO 22000, Kosher, and Halal, and does not use any non-food-grade chemical raw materials (such as colorants, flavorings, or additives) during processing.

MCP is extracted using patented biological enzymatic hydrolysis technology at an internationally leading level.

Numerous renowned scientists, universities, and research institutes around the world have conducted research on MCP.

Within China, research into low molecular weight pectin has been conducted by multiple universities since 2006, including Zhejiang University, Fudan University, Guangzhou Medical University, Tianjin University, and Xinxiang Medical University, among other institutions. Since 2012, Gold Kropn has collaborated with Zhejiang University and Fudan University on a series of functional studies of low molecular weight pectin, including its applications in inhibiting breast cancer, enhancing detoxification sensitization during chemotherapy, and removing heavy metals, all of which produced favorable results.

In 2017, Gold Kropn partnered with a U.S. company to conduct a clinical trial in Europe examining low molecular weight pectin as an intestinal prebiotic. The trial results confirmed that MCP promotes the growth of beneficial gut bacteria, with an effect that takes hold more than twice as fast as ordinary pectin. Detailed trial results are included in a new patent application to be filed at a later date.